周勤梅
一、个人简介:
周勤梅,博士学历、高级实验师、硕士生导师、成都中医药大学药学院。主要从事中药药性理论和药效物质基础研究。主持国家自然科学基金(广藿香“芳香”倍半萜治疗“湿浊带下”霉菌性阴道炎的药效物质与作用机制)、四川省自然科学基金(基于ca2 /camkⅱ/creb/bdnf信号通路研究“芳香化湿”药广藿香“醒脾解郁”的效应物质和作用机制)等各级项目5项;主研国家自然基金重点项目、国家自然基金面上项目、四川省杰出青年基金等项目。共发表学术论文40余篇,其中,以第一作者或通讯作者发表sci论文8篇、北大中文核心期刊论文10余篇,出版著作1部,获得授权发明专利7项。
二、代表性成果(可含承担项目、发表论文、论著、获奖等)
发表论文(#为第一作者,*为通讯作者):
1. qin-mei zhou#, hao-yu zhao#, chuan ma#, lu huang, jie liu, li guo, cheng peng*, liang xiong*. pocahemiketone a, a sesquiterpenoid possessing a spirocyclic skeleton with a hemiketal endoperoxide unit, alleviates aβ25-35-induced proptosis and oxidative stress in sh-sy5y cells[j]. organic letters, 2022, 24, 4734-4738.
2. lu huang, cheng peng*, li guo, rui feng, hong-zhen shu, yun-cai tian, qin-mei zhou*, liang xiong*. six pairs of enantiomeric phthalide dimers from the rhizomes of ligusticum chuanxiong and their absolute configurations and anti-inflammatory activities[j]. bioorganic chemistry, 2022, 127: 105970.
3. jing zuo#, tian-hao zhang#, liang xiong, lu huang, cheng peng, qin-mei zhou*, ou dai*. two pairs of 7,7′-cyclolignan enantiomers with anti-inflammatory activities from perilla frutescens[j]. molecules, 2022, 27: 6102.
4. hao‐yu zhao#, qin‐mei zhou#, huan zhu, fei zhou, chun‐wang meng, hong‐zhen shu, zhao‐hua liu, cheng peng*, liang xiong*. anisotanols a–d, four norsesquiterpenoids with an unprecedented sesquiterpenoid skeleton from anisodus tanguticus[j]. chinese journal of chemistry, 2021, 39: 3375-3380
5. fei zhou#, ou dai#, cheng peng*, liang xiong, hui ao, fei liu, qin-mei zhou*. pro-angiogenic effects of essential oil from perilla frutescens and its main component (perillaldehyde) on zebrafsh embryos and human umbilical vein endothelial cells[j]. drug design, development and therapy, 2021, 15: 4985-4999.
6. xiao-ya wang#, qin-mei zhou#, li guo, ou dai, chun-wang meng, lu-lin miao, jie liu, qiao lin, cheng peng*, liang xiong*. cardioprotective effects and concentration-response relationship of aminoalcohol-diterpenoid alkaloids from aconitum carmichaelii[j]. fitoterapia, 2021, 149: 104822.
7. qin-mei zhou#, ming-hua chen#, xiao-hong li, cheng peng*, da-sheng lin, xiao-nian li, yang he, liang xiong*. absolute configurations and bioactivities of guaiane-type sesquiterpenoids isolated from pogostemon cablin[j]. journal of natural products, 2018, 81(9): 1919-1927.
8. huan zhu#, qin-mei zhou#, cheng peng*, ming-hua chen, xiao-nian li, da-sheng lin, liang xiong*. pocahemiketals a and b, two new hemiketals with unprecedented sesquiterpenoid skeletons from pogostemon cablin[j]. fitoterapia, 2017, 120: 67-71.