裴瑾
个人简介:
裴瑾,博士,教授,博士生导师。西南特色中药资源国家重点实验室常务副主任,药学院/现代中药产业学院副院长。
国家中药种质资源库技术负责人,中药材标准化教育部重点实验室副主任。中华中医药学会中药鉴定专业委员会副会长,世界中医药学会联合会道地药材多维评价专业委员会秘书长,中国食品药品企业质量安全促进会区块链委员会副主任委员。四川省学术和技术带头人,四川省中医药学术和技术带头人,四川省中医药重点学科——药用植物学带头人,国家一流本科专业“中药资源与开发”负责人,规划教材《中药资源学》主编。
围绕中药资源可持续发展重大战略需求,从事中药资源保存与质量提升、道地药材品质形成机制和调控研究。构建我国中药种质低温保存技术体系,主持国家财政部、国家中医药管理局专项“中药种质资源库”、中药资源保障能力提升项目“中药资源战略性收集保存与保护”及四川省科技支撑计划“中药种质资源库建设关键技术研究及示范”等;主持“全国第四次中药资源普查四川2017-2019内业整理”,鉴定四川省46个县蜡叶标本13万份、药材3500余份、种苗2200余份;构建基于中药品质形成分子机制的“中药品质育种”研究策略,围绕红花、川牛膝、白芷等川产道地药材品质形成及新品种培育开展系统研究,主持国家自然科学基金“基于响应环境-调控合成功能基因解析红花有效成分积累的分子机制”“基于‘靶态’表型组与stacking集成学习解析番红花 ‘叶-种球’表里关系构建种球质量预测模型”、四川省“十四五”育种攻关“突破性道地中药材育种材料和方法创新及新品种选育——红花”等,挖掘中药品质特性功能基因、开展中药新品种选育,并指导生产;致力于中药标准化研究,主持/参与iso中医药国际标准“中药-西红花”“中药-红花”的制定及“泰国常用中药质量标准化”项目等。
在industrial crops & products、phytomedicine、bmc plant biology、药学学报、中国中药杂志等发表论文两百余篇,包括一区top、高被引论文;副主编“十二五”“十三五”国家重大出版工程项目《中国药用植物志》(第三卷)、《中国临床药物大辞典》(饮片卷、中药成方制剂卷),《新编中国药材学》(第七卷),2021年获中国政府出版奖。
代表性成果:
1、tao zhou, xue qiu, li zhao, weijing yang, feiyan wen, qinghua wu, jie yan, binjie xu, jiang chen, yuntong ma*, jin pei*.optimal light intensity and quality increased the saffron daughter corm yield by inhibiting the degradation of reserves in mother corms during the reproductive stage[j].industrial crops&products,2022,volume176.(q1,top)
2、tiexin zeng, xiao sun, yujing miao, shengjiugu, lixia tian, yan zheng, yuan jiang, xinkezhang, zhan feng, jin pei*, linfang huang *.integrating bioclimatic factors and secondary metabolism to predict the suitable producing area of plants with high specific metabolite content in a real-world environment - a case of carthamus tinctorius l.[j].industrial crops&products,2022,volume177.(q1,top)
3、bin xian, rui wang, huajuan jiang, yongfeng zhou, jie yan, xulong huang, jiang chen, qinghua wu, chao chen, ziqing xi, chaoxiang ren*, jin pei*.comprehensive review of two groups of flavonoids in carthamus tinctorius l.[j].biomed pharmacother. 2022 sep;153:113462. (q1)
4、lanyu zhou, lijie lu, chao chen, tao zhou, qinghua wu, feiyan wen, jiang chen, hugh w.pritchard, cheng peng, jin pei*and jie yan*.comparative changes in sugars and lipids show evidence of a critical node for regeneration in safflower seeds during aging. [j]. front. plant sci. 2022.13.(q1,top)
5、xu-long huang, hua-juan jiang, jin pei*, qing-hua wu*, wei-hua wu*, chao-xiang ren, lan-yu zhou, yong-feng zhou, bin xian, chao chen, yan-hang yan, li-jie lu, yue wang, xing-long zhu. study on the potential mechanism, therapeutic drugs and prescriptions of insomnia based on bioinformatics and molecular docking. [j].comput biol med., 2022 aug; 106001. (q1)
6、xiaominting song, huanan rao, chuanjie guo, bo yang, yali ren, miao wang, yuzhi li, zhixing cao*, jin pei*.myricetin exhibit selective anti-lymphoma activity by targeting btk and is effective via oral administration in vivo[j].phytomedicine,2021 dec;93:153802.(q2,top)
7、song x, tan l, wang m, ren c, guo c, yangb, ren y, cao z, li y*, pei j*. myricetin: a review of the most recent research[j].biomedicine & pharmacotherapy,2021 feb;134:111017.(q2,top,高被引)
8、shengju wang, huajuan jiang, qianqian liu, yongfeng zhou, yanfen cheng, tao zhou, jinming zhang, yao he, chaoxiang ren*, jinpei*.a comparative study on the traditional versus modern yellow rice wine processing methods using taohong siwu decoction for pharmaceutical productio[j].j ethnopharmacol. 2022 may 23;290:115114.(q2)
9、zhou y, niu m, zhang d, liu z, wu q, chen j, zhang h, zhang p*, pei j*. screening for anti-inflammation quality markers of lianhua qingwen capsule based on network pharmacology, uplc, and biological activity[j].frontiers in pharmacology,2021 jun 11;12:648439.(q2)
10、 chen j, wang j, wang r, xian b, ren c, liuq, wu q, pei j*.integrated metabolomics and transcriptome analysis on flavonoid biosynthesis in safflower (carthamus tinctorius l.) under meja treatment[j].bmc plant biol. 2020 jul 29;20(1):353.(q2)
11、 chen j, tang x, ren c, wei b, wu y, wu q, pei j*.full-length transcriptome sequences and the identification of putative genes for flavonoid biosynthesis in safflower[j].bmc genomics. 2018 jul 24;19(1):548.(q2)
12、 中药大品种康复新液系统创新及产业化关键技术研究应用,四川省科学技术进步一等奖,2016
13、 中药品质理论创建与实践,四川省科学技术进步二等奖,2012
14、 远志饮片炮制工艺及质量标准规范化研究,四川省科学技术进步二等奖,2008
15、 活血温里复方中温里药提高活血药生物利用度的研究,四川省科学技术进步三等奖,2006